What are the side effects of B12 1000 mcg?
Taking too much can cause side effects like nausea, headache, dizziness, and in rarely, blood clots or cancer. Everyone needs vitamin B-12, and most people get enough through their diet. However, it's important to know what side effects occur when you take too much.
Even the lowest doses in B12 supplements are many times the recommended dietary allowance. Doses up to 1,000 mcg, though unnecessary, aren't harmful. Fortified foods. Many breakfast cereals, soy products, and yeasts are fortified with B12.
A B12 ≥ 1000 ng/L was associated with the presence of solid cancer without metastases (OR 1.96 [95%CI: 1.18 to 3.25]) and with metastases (OR 4.21 [95%CI: 2.67 to 6.64]) after adjustment for all elevated B12-related causes.
Vitamin B12 supplements (along with other B vitamins) reduce blood levels of hom*ocysteine, a compound linked to an increased risk of having a heart attack or stroke.
- Headache.
- Nausea and vomiting.
- Diarrhea.
- Fatigue or weakness.
- Tingling sensation in hands and feet.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing. This is not a complete list of possible side effects.
This is particularly important if you experience any symptoms of high B12 levels in blood, including [9]: Gastrointestinal issues (like nausea, vomiting, and/or diarrhea) Headaches. Tingling in your hands and feet.
It's common to start treatment for a significant vitamin B12 deficiency with weekly intramuscular shots (1000 micrograms of vitamin B12). This bypasses any absorption problems in the stomach or intestine, and is a good way to get an older person's vitamin B12 level back to normal quickly.
One 2010 study found that people with diabetic nephropathy (loss of kidney function due to diabetes) experienced a more rapid decline in kidney function when supplemented with high dose B vitamins, including 1 mg per day of B12 ( 7 ).
An abnormally high vitamin B12 status is anything over 900 pg/mL . This result may suggest liver or kidney problems, diabetes, or certain forms of leukemia. Low. Levels of vitamin B12 are low if they are below 200 pg/mL .
How much B12 should a senior take daily?
How Much B12 Should Seniors Take? The amount of vitamin B12 that seniors should take depends on the level of need a given senior has; that's why it's important to involve medical professionals. In general, the recommended daily allowance is 2.4 mcg.
By taking supplements, you will ensure that your body absorbs vitamin B12. Additionally, there is no way that you will overdose on B12, so don't worry about taking too much.
You may be able to stop taking cyanocobalamin when your vitamin B12 blood levels are back to normal. However, you may need to take it for the rest of your life if your diet does not have enough vitamin B12 or you cannot absorb enough vitamin B12 from your food.
If you have any of the following health problems, consult your doctor or pharmacist before using this medication: a certain eye disease (Leber's optic neuropathy), a certain blood disorder (polycythemia vera), gout, iron or folic acid deficiency anemia, low potassium blood levels (hypokalemia).
Healthy doses of vitamin B12 strengthen your hair by helping your body absorb iron from food. Since iron is an important mineral for hair health, its better absorption makes a positive difference in your scalp. But, on the flip side, iron deficiency can lead to hair loss.
Gastrointestinal issues. A B12 deficiency may also cause diarrhea, nausea, constipation, bloating, gas, and other gastrointestinal symptoms ( 2 , 19 ). These issues can affect both adults and children ( 2 , 20 ).
Summary: As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).
Interactions between your drugs. No interactions were found between Vitamin B12 and Vitamin D3. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Other medications can also interfere with your uptake of vitamin B12, possibly raising your risk for deficiency. These medications include antacids and peptic ulcer medications, cholesterol-lowering drugs, antiseizure medications, chemotherapy medications, the diabetes treatment glucophage (Metformin) and others.
Avoid alcohol for 48 hours after your treatment. Avoid strenuous exercise for 48 hours after your treatment. Avoid touching the injection site for 6 hours after your treatment. You may experience a dull ache at the injections site for around 1 hour after your treatment.
Does B12 interfere with any medications?
Antibiotics, Tetracycline: Vitamin B12 should not be taken at the same time as tetracycline because it interferes with the absorption and effectiveness of this medication.
Reportedly, due to its low toxicity levels, no Tolerable Upper Intake Level (UL) has been established for B12. However, excess supplementation of vitamin B12 may lead to adverse effects on your body. Several studies reveal that too high doses of Vitamin B12 may lead to outbreaks of acne and rosacea.
The sudden increase in B12 can cause nausea, dizziness and headaches when first injected into the muscle. The human body is usually quick to adjust, though, so these symptoms should fade soon afterward. In rare cases, B12 can affect your potassium levels, causing muscle cramps or spasms.
1000 mcg is about 400 times as much as 2.4 mcg.
With that in mind, let's go back to our initial question: how much vitamin B12 should a person over 65 take? Recent reports suggest that, along with a B12-rich diet, consuming 500 micrograms of B12 in the form of a supplement may help individuals over 65 maintain healthy vitamin B12 levels [2].
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